@misc{Ziomkowska_Blanka_Deactivation_2006,
 author={Ziomkowska, Blanka and Kruszewski, Stefan and Siuda, Ryszard and Cyrankiewicz, Michał},
 contributor={Gaj, Miron. Redakcja and Wilk, Ireneusz. Redakcja},
 year={2006},
 rights={Wszystkie prawa zastrzeżone (Copyright)},
 description={Optica Applicata, Vol. 36, 2006, nr 1, s. 137-146},
 publisher={Oficyna Wydawnicza Politechniki Wrocławskiej},
 language={eng},
 abstract={Camptothecin is a fluorescent compound exhibiting strong anticancer properties. A serious limitation to clinical application of this compound is its hydrolysis, when biologically active lactone form converts into inactive carboxylate. There are some differences in the shapes of both fluorescence and absorption spectra of the lactone and carboxylate forms of camptothecin. Therefore, during hydrolysis resultant fluorescence and absorption spectra evolve. Factor analysis of fluorescence/absorption spectra recorded during the hydrolysis process of camptothecin enables one to determine the temporary concentration of the lactone and carboxylate forms and obtain the deactivation rate of this compound.},
 title={Deactivation rate of camptothecin determined by factor analysis of steady-state fluorescence and absorption spectra},
 type={artykuł},
 keywords={optyka, camptothecin, fluorescence, absorption, factor analysis},
}